‘St. Denis Medical’ Season 2 Trailer Teases New Hospital Shenanigans & Guest Stars (VIDEO)

The Season 2 return of NBC‘s comedy, St. Denis Medical, is quickly approaching, and the latest teaser is offering fans a glimpse into what stories they can anticipate from the upcoming chapter.
Along with St. Denis Medical‘s Season 2 slate of guest stars, NBC has revealed a premiere date and more exciting details about the hospital-set comedy’s return. Below, we’re breaking down everything you need to know about St. Denis Medical Season 2 so far, and stay tuned for additional details as they emerge in the weeks ahead.
When will St. Denis Medical Season 2 premiere?
Season 2 of St. Denis Medical will officially premiere on Monday, November 3, with back-to-back episodes airing at 8/7c on NBC.
Does St. Denis Medical Season 2 have a trailer?
Yes, the official trailer for St. Denis Medical Season 2 has been revealed, and it’s teasing upcoming guest stars, a therapy horse, and so much more. Watch the trailer here:
Who will star in St. Denis Medical Season 2?
Season 2 of the series will see the core characters from the mockumentary return, including Wendi McLendon-Covey as Joyce, David Alan Grier as Ron, Allison Tolman as Alex, Josh Lawson as Bruce, Kahyun Kim as Serena, Mekki Leeper as Matt, and Kaliko Kauahi as Val. Meanwhile, Love Island USA host and former Vanderpump Rules star Ariana Madix is set to guest star as Dr. Emerson. It has since been announced that Madix’s fellow Love Island USA colleague, Jeremiah Brown, would step in to guest star as Jeff, a handsome Ultimate Frisbee jock waiting for his roommate to be discharged from the hospital.

Ron Batzdorff / NBC; Courtesy of NBCUniversal
Additionally, it’s been announced that Kristen Schaal will guest star as Ashley, a “bookish sci-fi enthusiast” who has an unexpected meet-cute with a member of the St. Denis team. Lauren Weedman will play a retired charge nurse named Pam, who comes back to help out while St. Denis is understaffed. Frankie Quiñones will play Leslie, a security guard who is up on all of the hospital’s gossip. Lauren Lapkus has been tapped to play a pregnant woman accompanying her husband, played by Tim Baltz, to the hospital after a gender reveal party goes wrong. Rounding out the latest guest star announcements is Jonah Beckett, who will play Kyle, a college student whose mysterious illness is stumping the doctors at St. Denis.
What will St. Denis Medical Season 2 be about?
The series will likely continue to explore the day-to-day lives of the titular hospital’s staff as they tackle different cases of illness and injury. As an underfunded Oregon-based hospital, St. Denis Medical is the perfect catalyst for creating chaos regarding the staff, meaning there is no limit to the shenanigans its team can get up to.
Who makes St. Denis Medical Season 2?
St. Denis Medical is co-created and executive-produced by Eric Ledgin and Justin Spitzer. Meanwhile, Simon Heuer, Ruben Fleischer, Bridget Kyle, and Vicky Luu also serve as executive producers on the series, showrun by Ledgin. The series is produced for television by Universal Television, a division of Universal Studio Group, and Spitzer Holding Company.
Stay tuned for what’s in store on St. Denis Medical Season 2 as it takes shape.
St. Denis Medical, Season 2 Premiere, Monday, November 3, 8/7c, NBC