‘General Hospital’: Cameron Mathison Shares Update After Drew’s Shocking Shooting

Martin Holmes September 3, 2025, 9:02 am

Cameron Mathison is embracing playing the villainous scoundrel Drew Cain on General Hospital and is “super-excited” about being in the middle of a Port Charles whodunnit storyline.

Mathison took over the role of Congressman Andrew “Drew” Cain in 2021, a character who has taken a turn to the darkside over the past year, having affairs, blackmailing people, and even using his political power to destroy the Quartermaine family crypt. All that to say, Drew has amassed a long list of enemies who want to see him dead.

The character’s troublemaking finally caught up with him on Tuesday’s (September 2) episode, when he was shot in the back, twice, by a mystery assailant. The question now is, who shot Drew? For Mathison, he can’t wait to find out.

Speaking to Soap Opera Digest after the dramatic episode, Mathison explained why the show’s writers worked so hard on making Drew so despicable over the past few months, noting that it was all leading to this moment of comeuppance.

“Obviously, everybody hates me like crazy,” he said, noting how the storyline had been building up in recent months. Drew’s despicable behavior had gotten folks not liking him. Now things have taken a dramatic turn for the worse…enough to have someone try to kill him! Now the mystery is who shot Drew – and there are certainly plenty of suspects thew ay he has been making enemies.

The All My Children alum revealed that playing such a villain has been “weirdly therapeutic,” noting how it’s helped him escape some of the drama in his real life, which includes the end of his decades-long marriage and losing his home in the recent California wildfires.

“I try to be a really nice human and a good, solid person in my life and I’ve gone through a lot of big life challenges in a very short stretch of time,” he told Soap Opera Digest. “I go to work and get to be such a jerk — it’s almost like my little fantasy escape. I don’t know if it’s good for my psyche or not, but I’ve really leaned into it.”

Cameron Mathison as Drew Cain on General Hospital; Disney/Bahareh Ritter

Mathison admits he is always shocked and delighted by scripts and their twists and turns when he first gets to see them. “It’s been interesting and it’s been challenging.”

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The 56-year-old actor also spoke of his excitement about the Who Shot Drew storyline, comparing it to the iconic soap opera Dallas.

Back in 1980 Who Shot JR captivated TV fans around the world, including Mathison, who was then still at school. And he admits he’s relishing being GH‘s most hated character right now, as that keeps him front and center on the show.

As for the shooting scene itself, Mathison noted how he was “really excited” to take it on. “It’s not every day that you get to take a gunshot on camera, and I really wanted to get that right and fall hard,” he explained.

He’s loving that viewers wanted to see Drew get his comeuppance, but is staying tight-lipped about what happens next.

Who do you think shot Drew? Do you think he’ll survive the attack? Let us know your thoughts below.

General Hospital, Weekdays, ABC, Check local listings. Streaming on Hulu