20 Years Later, ‘Grey’s Anatomy’ Vet James Pickens Jr. Looks Back at Addison’s Debut

Grey’s Anatomy is celebrating 20 years on the air this year, and every fan remembers the scene when Dr. Addison Shepherd (Kate Walsh) set foot inside Seattle Grace and turned Meredith (Ellen Pompeo) and Derek’s (Patrick Dempsey) seemingly idyllic romance upside down.

With that fiery red hair and undeniable confidence, Addison walked right over to introduce herself, specifically to Meredith, “And you must be the woman who’s been screwing my husband.”