8 of the Greatest Sitcom Brothers & Sisters on National Sibling Day (PHOTOS)

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Malcolm, Reese, and Dewey Wilkerson (Malcolm in the Middle)

Reese may have been the household bully but he didn’t allow anyone at school to mess with Malcolm and Dewey—the least he could do after tormenting them himself. That loyalty and their elaborate pranks—the brothers were all smart in their own ways—made them fun to watch.

Drake and Josh
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Drake and Megan Parker; Josh Nichols (Drake and Josh)

Drake and Josh were an exceptional pair of step siblings. The two shared a room and always got into random shenanigans to keep their parents on their toes. Due to their alliance, sister Megan Parker became public enemy number one as she was seen as the spoiled angel by their parents.


Jordan, Bryana, and Vanessa Thomkins (The Bernie Mac Show)

Middle child Jordan was often picked on by both his sisters, as Nessa was older and stronger and Bryana was the sibling who could do no wrong. Still, they remained a tight-knit family under their strict Uncle Bernie, who took care of them after their mother went to rehab.


Maggie, Brighton, and Grace Sheffield (The Nanny)

Without these kids, there would be no show as after burning through a laundry list of nannies, the Sheffields found Fran Fine. Maggie was shy for a teenager, thus creating a closer bond with her much-younger but precocious sister Grace. Brighton was outside of the sister dynamic but still got along with the girls, nonetheless.


Lizzie and Matt McGuire (Lizzie McGuire)

The show largely focused on Lizzie navigating school, friends, and boys, but she and little brother Matt definitely had their funny moments. Lizzie was always getting annoyed with her little bro over his prankster personality—a stark contrast to her goodie-two-shoes ways.


Raven and Cory Baxter (That’s So Raven)

Raven and Cory both had huge personalities, which was a lot to contain under one roof but made for comedic gold when the two rivaled. You would think it would be hard to compete with a psychic older sister but fans loved Cory just as much—he even earned his own spinoff, Cory in the House.

8 Simple Rules – Martin Spanjers, Kaley Cuoco, Amy Davidson

Bridget, Kerry, and Rory Hennessy (8 Simple Rules)

Kerry and Bridget were stereotypical teen girls who did not get along—a feud based on brains versus brawn. Meanwhile, younger brother Rory was often the tattletale on his sisters. Clearly, they didn’t always get along but they did come together when it mattered, and it doesn’t get more realistic than that.


Michael Jr., Claire, and Kady Kyle (My Wife and Kids)

In the underrated sitcom, “Junior” was notorious for his big head with little intelligence inside, Claire for being extremely uncoordinated, and Kady for being seemingly innocent—except for with Claire. All of the kids were a bit ditsy, which raised the funny question of how they were even Michael and Jay’s kids.

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You know what they say about siblings—you can’t live with them and you can’t live without them.

These sets of brothers and sisters from sitcoms of the ’90s and early ’00s made us laugh with their family feuds and cry when they stood up for one another. These pairs were definitely #siblinggoals.

In honor of National Sibling Day (April 10), we’ve rounded up our favorites from Drake & Josh, Malcolm in the Middle, The Nanny, and more. Click through the gallery above for all the familial fun!