An elephant discovers a tiny community that lives on a dust mote.
Jim Carrey Horton
Steve Carell Mayor of Who-ville
Amy Poehler Salley O'Malley
Jesse McCartney Jo Jo
Isla Fisher Dr. Larue
Dan Fogler Yummo
Will Arnett Vlad
Seth Rogen Morton
Jonah Hill Tommy
Carol Burnett Kangaroo
Jaime Pressly Mrs. Quilligan