The Gallaghers Are Back in the 'Shameless' Season 10 Premiere (PHOTOS)

Rick and Christina Gables

When Season 10 of Shameless begins on Sunday November 10, the series picks up six months after last season’s finale: Frank (William H. Macy) uses his leg injury to collect as many prescription drugs as possible and his exploits lead him to an old friend.

Debbie (Emma Kenney), emboldened by the $50,000 left to her by Fiona, has stepped in as the new matriarch, ruling over the Gallagher household with an iron fist. Lip (Jeremy Allen White) navigates his relationship with a newly affectionate Tami (Kate Miner). Carl (Ethan Cutkosky) has to decide what to do with his life as he finishes military school and heads back to the South side.

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'Shameless' Boss on Where We Pick Up With the Gallaghers in Season 10

Find out how the South Side clan is faring after Fiona's departure.

Liam (Christian Isaiah) is committed to learning more about black history and culture under the tutelage of V (Shanola Hampton) as Kev (Steve Howey) faces an identity crisis. Gallavich returns this season as Ian (Cameron Monaghan) and Mickey (Noel Fisher) rekindle their romance in prison as both cellmates and lovers.

Click through the gallery above for a sneak peek at the premiere episode, "We Few, We Lucky Few, We Band of Gallaghers!"

Shameless, Season 10 Premiere, Sunday, November 10, 9/8c, Showtime