‘Grey’s Anatomy’ Texas-Set Spinoff Casts Karla Souza

Amanda Bell November 11, 2026, 1:32 pm

Celebrity Sightings In New York City - February 17, 2026 — Getty Images

What To Know

The first cast member for the upcoming Grey’s Anatomy spinoff set in Texas has been revealed.
Karla Souza, who previously starred in ShondaLand’s How to Get Away With Murder, will lead the cast of the new series.

Grey’s Anatomy fans might have to wait a bit longer than they might’ve hoped for the new Texas-set spinoff to arrive on ABC, but what we don’t have to wait on is some casting news.

Deadline reports that Karla Souza will lead the cast of the new series as Carolina “Lina” Hall, a character described as “a haunted and cynical doctor in her 40s who runs a medical center in a small town in West Texas.”

Souza, who previously headlined the fellow ShondaLand drama How to Get Away With Murder, is the first star to be attached to the series.

The still as-yet-untitled series will be set in rural Texas but filmed in Albuquerque, New Mexico, marking the first time a Grey’s show is produced outside of Hollywood, California. The move also resulted in a delay of its anticipated premiere from the midseason to the 2027 to 2028 schedule for ABC, after the executive producers were unable to secure a California tax credit due to it being a new series.

Matt McGorry as Asher Millstone, Karla Souza as Laurel Castillo, Alfred Enoch as Wes Gibbins, and Aja Naomi King as Michaela Pratt in 'How to Get Away With Murder'

Mitchell Haaseth / ABC / Everett Collection

The Grey’s Anatomy Texas spinoff is the fourth in the franchise, following Private Practice and Station 19, both of which have ended, and will be overseen by executive producers Shonda Rhimes, Betsy Beers, Meg Marinis, and Grey’s lead Ellen Pompeo.

'Grey's Anatomy' Showrunner Shares Texas Spinoff Update

Though the series is expected to be a standalone, Marinis has previously indicated that some alums of the Grey’s Anatomy TV universe might drop in for the story once in a while. In a recent interview with Deadline, she explained, “We’re still figuring out which episode, but yeah, just, traditionally with a spinoff [that’s done]. We’re still working out on timing…. We’re always open to bringing back old characters. One of the joys of having a Season 23 show is that you get to do that, and it’s also such a great gift to the fans. It always just depends on how much room we have creatively and people’s schedules because people leave the show and they go on to take other jobs, and it just gets tricky.”

Grey’s Anatomy, Thursdays, 10/9c, ABC