During the Great Depression, ex-boxer James J. Braddock (Russell Crowe) works as a day laborer until his former manager Joe Gould (Paul Giamatti) offers him a one-time slot against a rising young contender. After he wins a shocking upset, Braddock goes back into the ring full time, against the wishes of his frightened wife, Mae (Ren&233;e Zellweger). Dubbed "The Cinderella Man" for his rags-to-riches story, Braddock sets his sights on the defending champion, the fearsome Max Baer (Craig Bierko).
Annie (Kristen Wiig) is a single woman whose own life is a mess, but when she learns that her lifelong best friend, Lillian (Maya Rudolph), is engaged, she has no choice but to serve as the maid of honor. Though lovelorn and almost penniless, Annie, nevertheless, winds her way through the strange and expensive rituals associated with her job as the brides go-to gal. Determined to make things perfect, she gamely leads Lillian and the other bridesmaids down the wild road to the wedding.
John (Brad Pitt) and Jane Smith (Angelina Jolie), a couple in a stagnating marriage, live a deceptively mundane existence. However, each has been hiding a secret from the other: they are assassins working for adversarial agencies. When they are both assigned to kill the same target, Benjamin Danz (Adam Brody), the truth comes to the surface. Finally free from their cover stories, they discover that they have been assigned to kill each other, sparking a series of explosive attacks.